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Anaphylaxis Action Plan

Allergy Action Plan for the Treatment of Anaphylaxis

Anaphylaxis [anna-fih-LACK-sis] is a serious allergic reaction that can progress rapidly. It may involve multiple body organ systems. Epinephrine is the first-line treatment for anaphylaxis. People with food allergies should have a allergy action plan to help guide them on recognizing symptoms and prompt treatment to stop the reaction.

AAFA’s Allergy Anaphylaxis Action Plan provides information and instructions on how to manage an allergic reaction. It includes:

  • Symptoms to watch in infants/toddlers under age 3 or in people ages 3 and older (including children, teens, and adults)
  • Instructions for using epinephrine
  • What to do in an emergency
  • A guide to help you decide when to “watch and wait” and when to get emergency care

Take the form below to your doctor and have them fill it out and review it with you. If this plan is for your child, share it with schools, babysitters, and other caregivers.

Although the plan’s title states “Food Allergy”, it can be used for any allergy that is at risk of progressing to anaphylaxis. This is includes bee/wasp stings, drug allergies, latex allergy.

Symptoms of Serious Allergic Reactions (Anaphylaxis)

Signs and symptoms of anaphylaxis in children, teens, and adults include:

  • Skin rash, itching, hives
  • Swelling of the lips, tongue, or throat
  • Shortness of breath, trouble breathing, wheezing, coughing
  • Stomach pain, vomiting, diarrhea

Common signs and symptoms of anaphylaxis in infants and toddlers include:1

  • Skin rash, itching, hives
  • Swelling of the lips, tongue, or throat
  • Stomach pain, vomiting, diarrhea, spitting up
  • Tongue thrusting, tongue pulling, licking lips repeatedly, ear pulling
  • Arching back, bringing knees to the chest
  • Coughing, wheezing, hoarse voice, belly breathing, chest or neck “tugging”
  • Rubbing eyes, itchy or red eyes

Treatment for Anaphylaxis

Epinephrine works quickly and can stop the symptoms of a serious allergic reaction. It is important to use it immediately. Epinephrine is the only proven treatment for anaphylaxis to reduce the risk of hospital stays or even death.

The Asthma and Allergy Foundation of America has conducted or supported many studies on anaphylaxis. These studies helped experts identify symptoms of anaphylaxis in infants and toddlers, understand the use of epinephrine by parents and caregivers, and create the first validated food allergy anaphylaxis action plan.2
Medical Review: May 2025 by Matthew Greenhawt, MD, MBA, MSc
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References
  1. Pistiner, M., Mendez-Reyes, J. E., Eftekhari, S., Carver, M., Lieberman, J., Wang, J., & Camargo, C. A. (2021). Caregiver-reported presentation of severe food-induced allergic reactions in infants and toddlers. The Journal of Allergy and Clinical Immunology: In Practice, 9(1). https://doi.org/10.1016/j.jaip.2020.11.005

 

  1. Anagnostou, A., Abrams, E. M., Anderson, W. C., Carver, M., Eftekhari, S., Golden, D. B., Jaffee, H., Lieberman, J. A., Mack, D. P., Mustafa, S. S., Shaker, M. S., Spergel, J. M., Stukus, D. R., Wang, J., & Greenhawt, M. (2025). Development of a Validated, Updated North American Pediatric Food Allergy Anaphylaxis Management Plan. Annals of Allergy, Asthma & Immunology. Advance online publication. https://doi.org/10.1016/j.anai.2025.03.027
thumbnail image of poster that shows easy-to-use epinephrine options
A list of symptoms of an allergic reaction

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